Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 17/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 17/20 | 1.00 |
| ▸ | RELA | Q04206 | 17/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | CLPX | O76031 | 1/20 | 0.81 |
| ▸ | VCP | P55072 | 1/20 | 0.81 |
| ▸ | RORA | P35398 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Withaferin A SCHEMBL12309163 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL29398581 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL30782710 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL12309137 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL20136632 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL17807718 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL11950371 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL157208 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL18372363 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| SCHEMBL12309145 | 0.94 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369804-A1 | WITHANIA SOMNIFERA COMPOSITION, METHOD OF PREPARATION AND USE THEREOF | LAILA NUTRA PRIVATE LIMITED (IN) | 2021-12-02 | — | — | US | disclosed |