SCHEMBL15720840

SCHEMBL15720840

COc1cc(OS(C)(=O)=O)cc(C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.50
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
GAA P10253 2/20 0.45
ALDH1A1 P00352 1/20 0.45
KDM4E B2RXH2 2/20 0.43
CA12 O43570 1/20 0.43
CA3 P07451 1/20 0.43
PKM P14618 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
TSHR P16473 1/20 0.41
TAS2R14 Q9NYV8 1/20 0.41
PTGS2 P35354 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,5-Dimethoxybenzoic Acid SCHEMBL503889 0.84 RXRA (0.64) RXRACA1CA2GAAALDH1A1
SCHEMBL9957932 0.84 ALDH1A1 (0.55) CA1CA2GAAALDH1A1PKM
SCHEMBL9958096 0.84 ALDH1A1 (0.55) CA1CA2GAAALDH1A1PKM
SCHEMBL15720859 0.84 CA1 (0.47) CA1CA2GAAALDH1A1KDM4E
SCHEMBL2900339 0.83 KDM4E (0.43) CA1CA2GAAALDH1A1KDM4E
3,5-Dimethoxybenzoic Acid SCHEMBL5668197 0.82 RXRA (0.62) RXRACA1CA2GAAALDH1A1
3,5-Dimethoxybenzoic Acid SCHEMBL20592058 0.82 RXRA (0.62) RXRACA1CA2GAAALDH1A1
SCHEMBL30044171 0.81 TPMT (0.53) RXRATSHRPLA2G2A
SCHEMBL17653071 0.81 TPMT (0.39) CA1CA2ALDH1A1KDM4ECA12
SCHEMBL26146665 0.81 TPMT (0.53) RXRATSHRPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732063-B2 Kinase inhibitors RESPIVERT LIMITED (GB) 2017-08-15 US disclosed
EP-2925742-B1 KINASE INHIBITORS RESPIVERT LTD (GB) 2016-10-26 EP disclosed
US-20150329523-A1 KINASE INHIBITORS OXULAR ACQUISITIONS LIMITED (GB) 2015-11-19 US disclosed
EP-2925742-A1 KINASE INHIBITORS Respivert Limited (GB) 2015-10-07 EP disclosed
WO-2014076484-A1 KINASE INHIBITORS RESPIVERT LIMITED (GB) 2014-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150329523-A1 KINASE INHIBITORS SYK, SRC, BTK RXRA 2194/4885CA1 4759/4885CA2 3406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.