SCHEMBL15722840

SCHEMBL15722840

Cc1ccc(N(c2ccccc2)c2ccc(C(=O)c3ccc(N(c4ccccc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
LMNA P02545 2/20 0.61
SRD5A2 P31213 3/20 0.59
HPGD P15428 3/20 0.58
RAB9A P51151 3/20 0.58
NPC1 O15118 2/20 0.58
AKR1C3 P42330 1/20 0.55
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
MAPT P10636 1/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
HTT P42858 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13781088 0.96 HPGD (0.63) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL2742817 0.92 ALDH1A1 (0.73) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL19496754 0.90 SRD5A2 (0.66) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL19773619 0.90 SRD5A2 (0.56) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL18828187 0.90 SRD5A2 (0.56) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL329666 0.90 RAB9A (0.63) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL17284937 0.89 SRD5A2 (0.56) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL850988 0.89 ALDH1A1 (0.48) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL329499 0.88 RAB9A (0.67) ALDH1A1LMNASRD5A2HPGDRAB9A
SCHEMBL8684872 0.88 RAB9A (0.67) ALDH1A1LMNASRD5A2HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140141362-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-05-22 US disclosed
US-20140141362-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-05-22 US disclosed