SCHEMBL15722940

SCHEMBL15722940

C/C=C/Oc1ccc(-c2ccc(C)cc2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.33
PTGS1 P23219 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15726834 0.90 FFAR4 (0.37)
SCHEMBL15684601 0.85 ALOX5AP (0.36)
SCHEMBL15726854 0.85 FFAR1 (0.40)
SCHEMBL15682079 0.84 PTGS2 (0.36) PTGS2
SCHEMBL15722954 0.84 ALDH1A1 (0.36)
SCHEMBL15722955 0.83 ALDH1A1 (0.32)
SCHEMBL15722941 0.83 PTGDR2 (0.32)
SCHEMBL15726811 0.83 PRSS1 (0.40)
SCHEMBL12172445 0.82 PTGS2 (0.34) PTGS2PTGS1
SCHEMBL19604519 0.82 PTGS2 (0.37) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9193907-B2 Liquid crystal compound having vinyloxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-9193907-B2 Liquid crystal compound having vinyloxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20140138582-A1 LIQUID CRYSTAL COMPOUND HAVING VINYLOXY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-22 US disclosed
US-20140138582-A1 LIQUID CRYSTAL COMPOUND HAVING VINYLOXY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-22 US disclosed