SCHEMBL15723116

SCHEMBL15723116

C/C=C/Oc1ccc(CCc2ccc(-c3ccc(CCCCC)cc3)c(F)c2)c(F)c1F

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.45
RARA P10276 1/20 0.35
RARG P13631 1/20 0.35
S1PR1 P21453 4/20 0.35
S1PR3 Q99500 3/20 0.33
MPL P40238 2/20 0.32
HTR2A P28223 1/20 0.32
THRB P10828 2/20 0.31
THRA P10827 1/20 0.31
APAF1 O14727 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15723106 0.89 RARB (0.38) RARBRARARARGHTR2ATHRB
SCHEMBL15723185 0.89 RARB (0.38) RARBRARARARGHTR2ATHRB
SCHEMBL15722993 0.88 THRB (0.38) HTR2ATHRBTHRA
SCHEMBL15726818 0.87 BACE1 (0.34) S1PR1
SCHEMBL15723133 0.87 RARB (0.46) RARBRARARARGS1PR1S1PR3
SCHEMBL15723194 0.85 RARB (0.41) RARBRARARARGMPLHTR2A
SCHEMBL15722943 0.85 RARB (0.43) RARBRARARARGMPLHTR2A
SCHEMBL15722992 0.84 THRA (0.33) THRBTHRA
SCHEMBL15722945 0.84 RARB (0.44) RARBRARARARGHTR2ATHRB
SCHEMBL15722946 0.84 RARB (0.44) RARBRARARARGHTR2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9193907-B2 Liquid crystal compound having vinyloxy, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-11-24 US disclosed
US-20140138582-A1 LIQUID CRYSTAL COMPOUND HAVING VINYLOXY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-22 US disclosed