Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107731 | 0.89 | HDAC3 (0.36) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL18081560 | 0.89 | ALDH1A1 (0.37) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL12382220 | 0.87 | FOLH1 (0.35) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL2607947 | 0.87 | FOLH1 (0.33) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL12107740 | 0.85 | FOLH1 (0.38) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL14755921 | 0.85 | ALDH1A1 (0.35) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL16328730 | 0.85 | ALDH1A1 (0.39) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL18081559 | 0.85 | ALDH1A1 (0.35) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL15144373 | 0.85 | FOLH1 (0.34) | FOLH1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL14984422 | 0.85 | HDAC3 (0.40) | FOLH1POLBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9347054-B2 | Polymer factor IX moiety conjugates | NEKTAR THERAPEUTICS (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140141483-A1 | POLYMER FACTOR IX MOIETY CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-05-22 | — | — | US | disclosed |