Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311712 | 0.95 | ALDH1A1 (0.32) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL12107731 | 0.88 | HDAC3 (0.36) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL18081560 | 0.88 | ALDH1A1 (0.37) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL15725708 | 0.87 | FOLH1 (0.34) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL14755921 | 0.87 | ALDH1A1 (0.35) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL15144373 | 0.87 | FOLH1 (0.34) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL12382220 | 0.86 | FOLH1 (0.35) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL13225546 | 0.85 | HDAC3 (0.35) | POLBHSD17B10HDAC3HDAC4HDAC1 | |
| SCHEMBL16328730 | 0.84 | ALDH1A1 (0.39) | FOLH1POLBHSD17B10HDAC3HDAC4 | |
| SCHEMBL12107740 | 0.84 | FOLH1 (0.38) | FOLH1POLBHSD17B10HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9433684-B2 | Conjugates of small-interfering nucleic acids | NEKTAR THERAPEUTICS (US) | 2016-09-06 | — | — | US | disclosed |
| US-8586711-B2 | Polymer-factor IX moiety conjugates | NEKTAR THERAPEUTICS (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120100096-A1 | CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS | NEKTAR THERAPEUTICS (US) | 2012-04-26 | — | — | US | disclosed |
| US-20100160610-A1 | Conjugates of an EPO Moiety and a Polymer | NEKTAR THERAPEUTICS (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100120982-A1 | POLYMER-FACTOR IX MOIETY CONJUGATES | NEKTAR THERAPEUTICS (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120982-A1 | POLYMER-FACTOR IX MOIETY CONJUGATES | F9, F13A1, F13B | FOLH1 113/4885POLB 1496/4885HSD17B10 3318/4885 |
| US-20120100096-A1 | CONJUGATES PF SMALL-INTERFERING NUCLEIC ACIDS | SLC19A1, FOLR1, SLC46A1 | FOLH1 77/4885POLB 130/4885HSD17B10 3813/4885 |
| US-20100160610-A1 | Conjugates of an EPO Moiety and a Polymer | EPOR, EPRS1, NPPA | FOLH1 56/4885POLB 1603/4885HSD17B10 2603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.