Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | CCR5 | P51681 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.47 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20456336 | 0.93 | SLC6A4 (0.53) | SLC6A4CCR5LMNAUSP2ALDH1A1 | |
| SCHEMBL21042791 | 0.93 | SLC6A4 (0.53) | SLC6A4CCR5LMNAUSP2ALDH1A1 | |
| SCHEMBL31053305 | 0.92 | SLC6A4 (0.46) | SLC6A4CCR5LMNAUSP2ALDH1A1 | |
| SCHEMBL31053270 | 0.92 | SLC6A4 (0.46) | SLC6A4CCR5LMNAUSP2ALDH1A1 | |
| SCHEMBL31644088 | 0.87 | SLC6A4 (0.66) | SLC6A4CCR5LMNAALDH1A1RAB9A | |
| SCHEMBL368071 | 0.87 | SLC6A4 (0.66) | SLC6A4CCR5LMNAALDH1A1RAB9A | |
| SCHEMBL1516692 | 0.86 | FBP1 (0.44) | SLC6A4LMNAALDH1A1RAB9AHTR2C | |
| SCHEMBL31053304 | 0.86 | FBP1 (0.44) | SLC6A4LMNAALDH1A1RAB9AHTR2C | |
| SCHEMBL6044498 | 0.85 | LMNA (0.47) | SLC6A4CCR5LMNAUSP2ALDH1A1 | |
| SCHEMBL1447864 | 0.84 | SLC6A4 (0.59) | SLC6A4CCR5ALDH1A1RAB9ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841456-B2 | 1,5-naphthyridine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-09-23 | — | — | US | disclosed |
| US-8841456-B2 | 1,5-naphthyridine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20140142302-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-05-22 | — | — | US | disclosed |
| US-20140142302-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142302-A1 | 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF | NRAS, RAF1, KRAS | SLC6A4 4096/4885CCR5 3061/4885LMNA 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.