Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809920 | 0.91 | MAPT (0.43) | MAPT | |
| SCHEMBL19262493 | 0.83 | MAPT (0.48) | MAPTCYP1A2 | |
| SCHEMBL4957551 | 0.83 | MAPT (0.43) | MAPTDAO | |
| SCHEMBL20932920 | 0.82 | TSHR (0.33) | MAPTDAO | |
| SCHEMBL15728707 | 0.81 | MAPT (0.36) | MAPTCYP1A2DAO | |
| SCHEMBL15457901 | 0.80 | MAPT (0.54) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL13082034 | 0.79 | CYP1A2 (0.54) | MAPTCYP1A2DAOLMNAMAPK1 | |
| SCHEMBL8570161 | 0.79 | CYP1A2 (0.54) | MAPTCYP1A2DAOLMNAMAPK1 | |
| SCHEMBL4960222 | 0.79 | LMNA (0.39) | MAPTCYP1A2DAOLMNAMAPK1 | |
| SCHEMBL15368083 | 0.79 | MAPT (0.57) | MAPTCYP1A2LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178419-A1 | COMPOSITION FOR NANOENCAPSULATION AND NANOCAPSULES COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |
| US-20170292072-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-10-12 | — | — | US | disclosed |
| US-20170002267-A1 | Liquid Crystal Medium | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2016-12-15 | — | — | US | disclosed |
| US-20160333270-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-11-17 | — | — | US | disclosed |
| US-9388339-B2 | Liquid-crystalline medium, method for the stabilization thereof, and liquid-crystal display | MERCK PATENT GMBH (DE) | 2016-07-12 | — | — | US | disclosed |
| US-20160108318-A1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2016-04-21 | — | — | US | disclosed |
| US-20160046863-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-02-18 | — | — | US | disclosed |
| US-20160046862-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-02-18 | — | — | US | disclosed |
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150267119-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150203758-A1 | LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150175884-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-8999460-B2 | Compounds and liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-8962102-B2 | — | — | 2015-02-24 | — | — | US | disclosed |
| US-20140111730-A1 | Liquid-crystalline medium, method for the stabilization thereof, and liquid-crystal display | MERCK PATENT GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| US-20140028964-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| EP-1646703-B1 | LIQUID-CRYSTAL MEDIUM CONTAINING MONOFLUOROTERPHENYL COMPOUNDS | MERCK PATENT GMBH (DE) | 2010-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | LASP1, VCL, NEFM | MAPT 202/4885CYP1A2 4329/4885DAO 1144/4885 |
| US-20150267119-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | LPXN, VCL, LCP1 | MAPT 19/4885CYP1A2 3440/4885DAO 2563/4885 |
| US-20160362606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | MAPT 40/4885CYP1A2 3876/4885DAO 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.