Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 8/20 | 0.43 |
| ▸ | CA1 | P00915 | 8/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.43 |
| ▸ | CA9 | Q16790 | 8/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CHAT | P28329 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602564 | 0.90 | CHAT (0.44) | ENPP2POLBCA12CA1CA2 | |
| SCHEMBL11599622 | 0.90 | CA12 (0.54) | NPC1RAB9AENPP2POLBCA12 | |
| SCHEMBL2200140 | 0.90 | CA12 (0.54) | NPC1RAB9AENPP2POLBCA12 | |
| SCHEMBL14602563 | 0.89 | ENPP2 (0.46) | ENPP2POLBCA12CA1CA2 | |
| SCHEMBL1536256 | 0.88 | CA12 (0.56) | NPC1RAB9AENPP2CA12CA1 | |
| SCHEMBL1536252 | 0.88 | CA12 (0.53) | NPC1RAB9AENPP2POLBCA12 | |
| Potassium SCHEMBL2203007 | 0.88 | CA12 (0.53) | NPC1RAB9AENPP2POLBCA12 | |
| SCHEMBL11879462 | 0.88 | CA12 (0.53) | NPC1RAB9AENPP2POLBCA12 | |
| SCHEMBL18043806 | 0.88 | CA12 (0.47) | ENPP2POLBCA12CA1CA2 | |
| SCHEMBL2205601 | 0.88 | CA12 (0.47) | ENPP2POLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376405-B2 | Bis-(triazinylamino)-stilbene derivatives | CLARIANT INTERNATIONAL LTD (CH) | 2016-06-28 | — | — | US | disclosed |
| EP-2518058-B1 | Novel bis-(triazinylamino)-stilbene derivatives | CLARIANT INT LTD (CH) | 2014-10-29 | — | — | EP | disclosed |
| US-20140142305-A1 | NOVEL BIS-(TRIAZINYLAMINO)-STILBENE DERIVATIVES | CLARIANT INTERNATIONAL LTD (CH) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142305-A1 | NOVEL BIS-(TRIAZINYLAMINO)-STILBENE DERIVATIVES | TSN, SMARCB1, TXLNA | NPC1 3512/4885RAB9A 3250/4885SMN1; SMN2 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.