SCHEMBL15729971

SCHEMBL15729971

CCc1ccc(Cc2cn(-c3ccccc3)nn2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.64
CD74 P04233 1/20 0.64
L3MBTL1 Q9Y468 3/20 0.57
NOTUM Q6P988 2/20 0.57
MAOA P21397 1/20 0.57
PTGS2 P35354 1/20 0.50
GSK3B P49841 2/20 0.49
CDC7 O00311 1/20 0.49
AURKA O14965 1/20 0.49
CHUK O15111 1/20 0.49
DAPK3 O43293 1/20 0.49
JAK2 O60674 1/20 0.49
ROCK2 O75116 1/20 0.49
CHEK2 O96017 1/20 0.49
CDK1 P06493 1/20 0.49
PIM1 P11309 1/20 0.49
PRKACA P17612 1/20 0.49
CDK2 P24941 1/20 0.49
MARK3 P27448 1/20 0.49
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3777938 0.83 NOTUM (0.68) MIFCD74L3MBTL1NOTUMMAOA
Bromide SCHEMBL1882333 0.82 NOTUM (0.66) MIFCD74L3MBTL1NOTUMMAOA
SCHEMBL17910076 0.78 MIF (0.73) MIFCD74L3MBTL1NOTUMMAOA
SCHEMBL2757866 0.78 MIF (1.00) MIFCD74L3MBTL1NOTUMMAOA
SCHEMBL12420291 0.78 S1PR1 (0.59) PTGS2CDC7NPC1RAB9ASMN1; SMN2
SCHEMBL12601113 0.77 NOTUM (0.64) MIFCD74L3MBTL1NOTUMMAOA
Bromide SCHEMBL1894577 0.76 NOTUM (0.62) MIFCD74L3MBTL1NOTUMMAOA
SCHEMBL18965360 0.76 NOTUM (0.62) MIFCD74L3MBTL1NOTUMMAOA
SCHEMBL15075954 0.74 L3MBTL1 (0.55) MIFCD74L3MBTL1NOTUMMAOA
SCHEMBL15076068 0.74 L3MBTL1 (0.55) MIFCD74L3MBTL1NOTUMMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447245-B2 Cross-linking and stabilization of organic metal complexes in networks CYNORA GMBH (DE) 2016-09-20 US disclosed
US-20140142258-A1 CROSS-LINKING AND STABILIZATION OF ORGANIC METAL COMPLEXES IN NETWORKS CYNORA GMBH (DE) 2014-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142258-A1 CROSS-LINKING AND STABILIZATION OF ORGANIC METAL COMPLEXES IN NETWORKS SOD1, MTCL3, LIG4 MIF 889/4885CD74 679/4885L3MBTL1 3260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.