SCHEMBL15730458

SCHEMBL15730458

Cc1ccc(-c2cc3c(C)c(C)c4cc(-c5ccc(C)s5)sc4c3s2)s1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 2/20 0.37
GFER P55789 1/20 0.37
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
RXFP1 Q9HBX9 2/20 0.33
PGR P06401 1/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19267427 0.82 NPC1 (0.36) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL18195316 0.79 NPC1 (0.38) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL18195309 0.77 NPC1 (0.33) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12711920 0.77 PGR (0.33) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL14854124 0.77 NPC1 (0.42) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL29764 0.76 NPC1 (0.52) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL18133629 0.76 NPC1 (0.39) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL12279105 0.76 NPC1 (0.39) NPC1ALDH1A1HSD17B10MAPTGFER
SCHEMBL25450806 0.76 PTGS2 (0.43) NPC1ALDH1A1HSD17B10MAPTMEN1
SCHEMBL12711996 0.76 PGR (0.35) NPC1ALDH1A1HSD17B10MAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006725-B2 Dithienophthalimide semiconductor polymers BASF SE (DE) 2015-04-14 US disclosed
US-20140142265-A1 DITHIENOPHTHALIMIDE SEMICONDUCTOR POLYMERS BASF (DE) 2014-05-22 US disclosed