Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15732176 | 0.86 | OPRM1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL15732210 | 0.83 | OPRM1 (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16747749 | 0.77 | OPRK1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14996104 | 0.77 | OPRK1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL19322785 | 0.77 | OPRM1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL15214352 | 0.77 | OPRK1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL17233018 | 0.75 | OPRM1 (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL15732229 | 0.72 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL15732201 | 0.72 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL15732232 | 0.72 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853232-B2 | Peripheral opioid receptor antagonists and uses thereof | WYETH LLC (US) | 2014-10-07 | — | — | US | disclosed |
| US-20140142132-A1 | PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF | WYETH, LLC (US) | 2014-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142132-A1 | PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF | OPRM1, OPRL1, OPRK1 | OPRM1 1/4885OPRD1 4/4885OPRK1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.