Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512025 | 0.93 | ALDH1A1 (0.37) | ALDH1A1HTTMEN1KMT2AHPGD | |
| SCHEMBL4518702 | 0.92 | MEN1 (0.38) | ALDH1A1AKR1C2AKR1C1HTTNR1H4 | |
| SCHEMBL1573171 | 0.91 | NR1H4 (0.42) | ALDH1A1AKR1C2AKR1C1NR1H4MEN1 | |
| SCHEMBL1573416 | 0.90 | ALDH1A1 (0.38) | ALDH1A1AKR1C2AKR1C1HTTNR1H4 | |
| SCHEMBL1573017 | 0.88 | F10 (0.39) | ALDH1A1AKR1C2AKR1C1NR1H4MEN1 | |
| SCHEMBL13918726 | 0.87 | F10 (0.38) | ALDH1A1AKR1C2AKR1C1NR1H4MEN1 | |
| SCHEMBL4522090 | 0.87 | LMNA (0.39) | ALDH1A1AKR1C2AKR1C1HTTMEN1 | |
| SCHEMBL13918698 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL1572822 | 0.87 | F10 (0.38) | ALDH1A1AKR1C2AKR1C1NR1H4MEN1 | |
| SCHEMBL150004 | 0.86 | MAPT (0.46) | ALDH1A1MEN1KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018165-B1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI AVENTIS (FR) | 2011-04-13 | — | — | EP | disclosed |
| EP-2018165-A1 | FGF-PECEPTOR AGONIST DIMERIC COMPOUNDS | Sanofi-Aventis (FR) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007080325-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2007-07-19 | — | — | WO | disclosed |