SCHEMBL15733738

SCHEMBL15733738

CCO[Si](C)(C)c1ccc(-c2cccc(F)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.47
ESR2 Q92731 1/20 0.46
CYP11B2 P19099 2/20 0.45
CYP17A1 P05093 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP11B1 P15538 1/20 0.45
PTPN1 P18031 1/20 0.40
GRM5 P41594 1/20 0.38
HTR2C P28335 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
GRM2 Q14416 1/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38
NOTUM Q6P988 1/20 0.37
NT5E P21589 2/20 0.37
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15738306 0.88 TAAR1 (0.47) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15735356 0.86 TAAR1 (0.49) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15735739 0.85 FGFR1 (0.37) CYP17A1CYP11B1NOTUM
SCHEMBL15738879 0.83 NPC1 (0.39) CYP17A1TRPM8
SCHEMBL15736582 0.83 ESR2 (0.49) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15738693 0.82 TAAR1 (0.50) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15738026 0.82 TAAR1 (0.45) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15734692 0.82 MAOB (0.48) CA12CA9NOTUM
SCHEMBL15735017 0.82 TAAR1 (0.45) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL15736416 0.82 ACHE (0.38) TAAR1TRPM8NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
CN-107141313-A Transparent oxide electrode and its production method that surface modifier, surface for transparent oxide electrode are modified 信越化学工业株式会社 2017-09-08 CN disclosed
CN-103848859-A Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing same SHINETSU CHEMICAL CO 2014-06-11 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed