Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271018 | 0.84 | HSD11B1 (0.54) | MAPK14CHRNA7HTR3AHSD11B1 | |
| Hydrochloric Acid SCHEMBL4229087 | 0.83 | HSD11B1 (0.53) | MAPK14CHRNA7HTR3AHSD11B1 | |
| SCHEMBL1572573 | 0.80 | CNR2 (0.53) | CNR2CHRNA7HTR3A | |
| SCHEMBL3947809 | 0.73 | MGLL (0.62) | CNR2MGLLMAPK14CCR3CCR5 | |
| SCHEMBL2216397 | 0.72 | MAPK14 (0.64) | CNR2MGLLMAPK14CCR3CCR5 | |
| SCHEMBL4030623 | 0.72 | HSD11B1 (0.52) | CNR2MGLLMAPK14CHRNA7CCR3 | |
| SCHEMBL16002958 | 0.71 | MAPK14 (0.56) | CNR2MGLLMAPK14CCR3CCR5 | |
| SCHEMBL3210544 | 0.70 | MAPK14 (0.65) | MGLLMAPK14CCR5 | |
| SCHEMBL2036317 | 0.70 | MAPK14 (0.62) | MGLLMAPK14CCR3CCR5 | |
| SCHEMBL1572778 | 0.70 | CHRNA7 (0.52) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745046-B1 | 1 H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZIOSOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2011-04-13 | — | — | EP | claimed |