SCHEMBL15735490

SCHEMBL15735490

CCO[Si](C)(CCCc1ccc(C(F)(F)F)cc1)OCC

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
MAOB P27338 2/20 0.39
IDO1 P14902 2/20 0.39
FDFT1 P37268 2/20 0.38
MIF P14174 1/20 0.37
DAO P14920 2/20 0.36
PPARD Q03181 1/20 0.36
PPARA Q07869 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15737709 0.95 HDAC1 (0.42) TAAR1HDAC1HDAC8MAOBIDO1
SCHEMBL15738697 0.94 HDAC1 (0.41) TAAR1HDAC1HDAC8MAOBIDO1
SCHEMBL15735416 0.94 HDAC1 (0.41) TAAR1HDAC1HDAC8MAOBIDO1
SCHEMBL15734329 0.90 TAAR1 (0.46) TAAR1MAOBIDO1MIFDAO
SCHEMBL15734948 0.88 TAAR1 (0.43) TAAR1HDAC1HDAC8MAOBIDO1
SCHEMBL1637619 0.87 LPL (0.36)
SCHEMBL15738263 0.86 HDAC1 (0.42) TAAR1HDAC1HDAC8MAOBIDO1
SCHEMBL15737254 0.86 TAAR1 (0.44) TAAR1HDAC1HDAC8MAOBIDO1
SCHEMBL15738172 0.84 IDO1 (0.39) IDO1DAO
SCHEMBL15734316 0.84 TAAR1 (0.46) TAAR1HDAC1HDAC8MAOBIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed