SCHEMBL1637619

SCHEMBL1637619

CCO[Si](C)(CCCc1ccc(CCC[Si](C)(OCC)OCC)cc1)OCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 6/20 0.36
LIPG Q9Y5X9 6/20 0.36
ALDH1A1 P00352 3/20 0.35
ESR1 P03372 2/20 0.35
ADRA2A P08913 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
TACR2 P21452 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
SHBG P04278 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
HSPD1 P10809 1/20 0.35
ADRB3 P13945 1/20 0.35
HTR2C P28335 1/20 0.35
HSPE1 P61604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15737388 0.91 POLB (0.39) ALDH1A1HPGD
SCHEMBL7858996 0.91 MAOB (0.44) ALDH1A1HSD17B10KDM4ECYP3A4HTR2A
SCHEMBL1067547 0.90 CHRM2 (0.43) ADRA2ASLC6A2SLC6A4SLC6A3CHRM2
SCHEMBL3913283 0.89 HRH1 (0.43) ALDH1A1KDM4ELMNACYP3A4
SCHEMBL6557362 0.87
SCHEMBL16062863 0.87 CYP4F2 (0.36) LPLLIPGCA2
SCHEMBL15735490 0.87 TAAR1 (0.43)
SCHEMBL15505279 0.87 ALDH1A1 (0.34) ALDH1A1CA1CA2THRATHRB
SCHEMBL15734343 0.86 POLB (0.38) ALDH1A1HPGD
SCHEMBL15737330 0.84 POLB (0.37) LPLLIPGALDH1A1ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed