Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698665 | 1.00 | KDM4E (0.44) | KDM4EADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL697764 | 1.00 | KDM4E (0.44) | KDM4EADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1573465 | 0.83 | ADRA2C (0.41) | KDM4EADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1574207 | 0.83 | ADRA2C (0.41) | KDM4EADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL698523 | 0.83 | ADRA2C (0.41) | KDM4EADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1573551 | 0.83 | ADRA2C (0.41) | KDM4EADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL698793 | 0.81 | KMT2A (0.50) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL698574 | 0.81 | KMT2A (0.50) | ADRA2AADRA2BADRA2CADRA1AADRA1B | |
| SCHEMBL704577 | 0.78 | ADRA2A (0.38) | KDM4EADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL1573467 | 0.78 | ADRA2A (0.38) | KDM4EADRA2AADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | claimed |