SCHEMBL15736730

SCHEMBL15736730

CC[Si](Cc1ccccc1)(CC(F)F)OC(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
PPARG P37231 2/20 0.31
PPARA Q07869 2/20 0.31
TP53 P04637 1/20 0.31
TACR1 P25103 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15737143 0.74 NR1H2 (0.34) NR1H2NR1H3PPARGPPARATP53
SCHEMBL27959423 0.72 NR1H2 (0.37) NR1H2NR1H3PPARGPPARATP53
SCHEMBL15734840 0.72 IDO1 (0.30)
SCHEMBL15734891 0.71 NR1H2 (0.40) NR1H2NR1H3PPARGPPARATP53
SCHEMBL534084 0.69 TP53 (0.42) TP53
SCHEMBL15734615 0.69 NR1H2 (0.36) NR1H2NR1H3PPARGPPARA
SCHEMBL15734182 0.69 NR1H2 (0.38) NR1H2NR1H3PPARGPPARA
SCHEMBL534586 0.68 TP53 (0.41) TP53
SCHEMBL2838066 0.67 NR1H2 (0.33) NR1H2NR1H3
SCHEMBL15734758 0.66 NR1H2 (0.33) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed