SCHEMBL15737445

SCHEMBL15737445

CCCO[SiH](OCCC)c1ccc(-c2ccc(F)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
RARB P10826 3/20 0.37
RARA P10276 2/20 0.37
RARG P13631 1/20 0.35
GCGR P47871 1/20 0.33
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GRIN2B Q13224 3/20 0.32
APLNR P35414 1/20 0.32
USP7 Q93009 1/20 0.32
MGLL Q99685 2/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
KIF11 P52732 1/20 0.31
GRIN1 Q05586 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15734061 0.87 RARB (0.35) RARBRARARARG
SCHEMBL15735782 0.87 CYP17A1 (0.40) CYP17A1CYP11B1CYP11B2RARBRARA
SCHEMBL15733810 0.86 HPGD (0.34) HPGDTSHR
SCHEMBL15738881 0.83 BCL2L1 (0.38) RARBGCGR
SCHEMBL15736915 0.83 FFAR1 (0.34) RARB
SCHEMBL15735741 0.82 HDAC3 (0.35) CYP17A1CYP11B1RARBRARA
SCHEMBL15733741 0.81 TAAR1 (0.50) CYP17A1CYP11B1CYP11B2MGLL
SCHEMBL15737449 0.79 MAOA (0.31) GCGR
SCHEMBL704584 0.78 ALDH1A1 (0.35) LMNAHPGDTSHR
SCHEMBL15738433 0.77 FFAR1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed