SCHEMBL15739416

SCHEMBL15739416

Brc1cccc(-c2ccc3c(c2)c2ccc4ccccc4c2n3-c2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.36
EGFR P00533 1/20 0.36
ERBB2 P04626 1/20 0.36
MGAM O43451 2/20 0.35
GAA P10253 2/20 0.35
SI P14410 2/20 0.35
MGAM2 Q2M2H8 2/20 0.35
BIRC5 O15392 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
DCTPP1 Q9H773 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15739322 0.99 ABCG2 (0.35) ABCG2EGFRERBB2MGAMGAA
SCHEMBL15739411 0.91 EGFR (0.40) EGFRERBB2MGAMGAASI
SCHEMBL15739327 0.91 ABCG2 (0.36) ABCG2EGFRERBB2MGAMGAA
SCHEMBL15739334 0.90 ABCG2 (0.36) ABCG2EGFRERBB2MGAMGAA
SCHEMBL19152278 0.90 EGFR (0.39) EGFRERBB2NPC1RAB9AKDM4E
SCHEMBL15739315 0.89 EGFR (0.37) EGFRERBB2MGAMGAASI
SCHEMBL15739430 0.89 TDP1 (0.38) BIRC5NPC1RAB9AMMP2MMP9
SCHEMBL16985767 0.88 EGFR (0.38) EGFRERBB2NPC1RAB9AKDM4E
SCHEMBL19213872 0.88 MEN1 (0.36) ABCG2EGFRERBB2GAAKDM4E
SCHEMBL12126569 0.87 L3MBTL1 (0.41) EGFRERBB2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017123008-A1 ORGANIC LIGHT-EMITTING DEVICE, ORGANIC LIGHT-EMITTING DISPLAY DEVICE, AND COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE 덕산네오룩스 주식회사 2017-07-20 WO disclosed
US-9515269-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2016-12-06 US disclosed
US-9515269-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2016-12-06 US disclosed
US-20160293846-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-10-06 US disclosed
US-20160293846-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-10-06 US disclosed
WO-2014077558-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE FOR SAME 덕산하이메탈(주) (KR) 2014-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160293846-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF OR51E2, NFE2L2, ORAI2 ABCG2 4607/4885EGFR 971/4885ERBB2 3403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.