Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 2/20 | 0.30 |
| ▸ | UBE2N | P61088 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | IDE | P14735 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15739490 | 0.98 | CRHR1 (0.31) | TACR1 | |
| SCHEMBL15981331 | 0.97 | CRHR1 (0.32) | — | |
| SCHEMBL15739506 | 0.88 | LMNA (0.33) | TACR1 | |
| SCHEMBL14389954 | 0.88 | — | — | |
| SCHEMBL5624474 | 0.84 | TACR1 (0.33) | TACR1SGMS1SGMS2BCHEACHE | |
| SCHEMBL5623860 | 0.83 | TACR1 (0.33) | TACR1SGMS1SGMS2APAF1UBE2N | |
| SCHEMBL4361019 | 0.83 | CETP (0.38) | — | |
| SCHEMBL15981910 | 0.83 | CETP (0.31) | TACR1UBE2NIDE | |
| SCHEMBL5626270 | 0.82 | TACR1 (0.32) | TACR1SGMS1SGMS2BCHEACHE | |
| SCHEMBL15739594 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014128564-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-08-28 | — | — | WO | disclosed |
| WO-2014076568-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-05-22 | — | — | WO | disclosed |