Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705393 | 1.00 | POLB (0.33) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL696906 | 0.92 | LMNA (0.32) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL1573714 | 0.90 | LMNA (0.33) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL699093 | 0.89 | ALDH1A1 (0.40) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL697207 | 0.89 | PIM1 (0.31) | POLBLMNASSTR4SSTR1 | |
| SCHEMBL696887 | 0.87 | JMJD6 (0.34) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL698866 | 0.86 | SSTR4 (0.34) | POLBALDH1A1MAPTLMNASSTR4 | |
| SCHEMBL698720 | 0.85 | LMNA (0.32) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL697702 | 0.85 | MAPK1 (0.43) | POLBALDH1A1MAPTLMNATP53 | |
| SCHEMBL697281 | 0.84 | LMNA (0.32) | POLBALDH1A1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |