Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134201 | 0.83 | HPGD (0.43) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL9134199 | 0.83 | HPGD (0.43) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL23179960 | 0.81 | CTSD (0.41) | CTSDHPGDALDH1A1NPC1XBP1 | |
| SCHEMBL9134939 | 0.77 | CTSD (0.46) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL9134948 | 0.77 | CTSD (0.46) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL30210823 | 0.74 | CA1 (0.46) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL19671103 | 0.74 | CA1 (0.46) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL2120412 | 0.74 | CA1 (0.46) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL470307 | 0.74 | CA1 (0.46) | CTSDHPGDALDH1A1ABCG2NPC1 | |
| SCHEMBL4035904 | 0.74 | CA1 (0.46) | CTSDHPGDALDH1A1ABCG2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014078778-A2 | ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |