Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134201 | 1.00 | HPGD (0.43) | HPGDALDH1A1ABCG2CTSDXBP1 | |
| SCHEMBL15740322 | 0.83 | CTSD (0.41) | HPGDALDH1A1ABCG2CTSDXBP1 | |
| SCHEMBL4035904 | 0.79 | CA1 (0.46) | HPGDALDH1A1ABCG2CTSDCA1 | |
| SCHEMBL30210823 | 0.79 | CA1 (0.46) | HPGDALDH1A1ABCG2CTSDCA1 | |
| SCHEMBL19671103 | 0.79 | CA1 (0.46) | HPGDALDH1A1ABCG2CTSDCA1 | |
| SCHEMBL2120412 | 0.79 | CA1 (0.46) | HPGDALDH1A1ABCG2CTSDCA1 | |
| SCHEMBL470307 | 0.79 | CA1 (0.46) | HPGDALDH1A1ABCG2CTSDCA1 | |
| SCHEMBL9133847 | 0.78 | MAPT (0.54) | HPGDALDH1A1ABCG2CA1CA2 | |
| SCHEMBL9133854 | 0.78 | MAPT (0.54) | HPGDALDH1A1ABCG2CA1CA2 | |
| SCHEMBL11374971 | 0.75 | NOS3 (0.47) | HPGDALDH1A1ABCG2CTSDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378702-A | Thiadizinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-01-03 | — | — | US | disclosed |