Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.70 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 5/20 | 0.58 |
| ▸ | BRD4 | O60885 | 6/20 | 0.58 |
| ▸ | BRD2 | P25440 | 6/20 | 0.58 |
| ▸ | BRD3 | Q15059 | 6/20 | 0.58 |
| ▸ | CCKAR | P32238 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574634 | 0.91 | SENP1 (0.73) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL6940307 | 0.91 | SENP1 (0.73) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL8711261 | 0.88 | SENP1 (0.79) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL8711263 | 0.88 | SENP1 (0.79) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL8939417 | 0.88 | SENP1 (0.79) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL9865538 | 0.88 | SENP1 (0.73) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL8939498 | 0.88 | SENP1 (0.73) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL9868194 | 0.87 | SENP1 (0.71) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL9865718 | 0.86 | SENP1 (0.76) | SENP1SCN9ACCKBRBRD4BRD2 | |
| SCHEMBL1574343 | 0.86 | SENP1 (0.75) | SENP1SCN9ACCKBRBRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342719-B1 | Benzodiazepine derivatives useful as CCK-Receptor Antagonists | FERRING BV (NL) | 2011-04-13 | — | — | EP | disclosed |
| EP-1342719-A1 | Benzodiazepine derivatives useful as CCK-Receptor Antagonists | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
| EP-0628033-B1 | BENZODIAZEPIN DERIVATIVES USEFUL AS CCK-RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMA CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5962451-A | GASTROINTESTINAL DISORDERS; ANTIULCER AGENT; ANTICANCER AGENTS; SIDE-EFFECT REDUCTION | FERRING BV (NL) | 1999-10-05 | — | — | US | disclosed |
| US-5688943-A | CHOLECYSTOKININ ANTAGONIST; ANTIULCER AGENTS; PSYCHOLOGICAL DRUGS; ANXIOLYTIC AGENTS; CONTROLLING APPETITE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0628033-A1 | BENZODIAZEPIN DERIVATIVES USEFUL AS CCK-RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993016999-A1 | BENZODIAZEPIN DERIVATIVES USEFUL AS CCK-RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |