Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30236658 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL29559882 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL22866816 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5972769 | 0.83 | MAPT (0.47) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL21930097 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL18704585 | 0.81 | KDM4E (0.46) | SMN1; SMN2MEN1KMT2ARAB9ATDP1 | |
| SCHEMBL16555251 | 0.81 | SLC6A4 (0.49) | SMN1; SMN2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL1702264 | 0.80 | MAPK1 (0.40) | SMN1; SMN2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL29581989 | 0.80 | MAPK1 (0.40) | SMN1; SMN2MEN1KMT2AMAPTTDP1 | |
| SCHEMBL31641561 | 0.79 | HTR7 (0.60) | SMN1; SMN2MAPTALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552793-B2 | Purine derivative and medical use thereof | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2026-02-17 | — | — | US | disclosed |
| CN-113121538-B | Furan derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-113121574-B | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| US-20220402920-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
| EP-4086258-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) | 2022-11-09 | — | — | EP | disclosed |
| CN-113121574-A | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-113121538-A | Furan derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
| WO-2021136462-A1 | FURAN DERIVATIVES AND APPLICATION THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |
| WO-2021136462-A1 | FURAN DERIVATIVES AND APPLICATION THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |
| WO-2021136463-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |
| WO-2021136463-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |
| US-9499497-B2 | Compounds useful as inhibitors of indoleamine 2,3-dioxygenase | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150336903-A1 | COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-11-26 | — | — | US | disclosed |
| EP-2922847-A1 | COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | Vertex Pharmaceuticals Incorporated (US) | 2015-09-30 | — | — | EP | disclosed |
| US-9073875-B2 | Compounds useful as inhibitors of indoleamine 2,3-dioxygenase | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140179699-A1 | COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | VERTEX PHARMACEUTICALS INCORPORATED | 2014-06-26 | — | — | US | disclosed |
| WO-2014081689-A1 | COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552793-B2 | Purine derivative and medical use thereof | PNP, CYP2D6, ADORA1 | SMN1; SMN2 1836/4885MEN1 2621/4885KMT2A 2837/4885 |
| US-20150336903-A1 | COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | SMN1; SMN2 3267/4885MEN1 954/4885KMT2A 518/4885 |
| US-20140179699-A1 | COMPOUNDS USEFUL AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | SMN1; SMN2 3267/4885MEN1 954/4885KMT2A 518/4885 |
| US-20220402920-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | DPYD, PNP, TYMP | SMN1; SMN2 2924/4885MEN1 2738/4885KMT2A 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.