Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740416 | 0.90 | TMEM97 (0.34) | TMEM97MAPK1NPSR1SUV39H2 | |
| SCHEMBL15740369 | 0.90 | TMEM97 (0.34) | TMEM97MAPK1NPSR1SUV39H2 | |
| SCHEMBL15740401 | 0.86 | TMEM97 (0.37) | TMEM97MAPK1NPSR1 | |
| SCHEMBL15740430 | 0.85 | MAPK1 (0.37) | TMEM97MAPK1NPSR1 | |
| SCHEMBL15724839 | 0.84 | TMEM97 (0.34) | TMEM97MAPK1NPSR1SUV39H2 | |
| SCHEMBL15708167 | 0.84 | TMEM97 (0.34) | TMEM97MAPK1NPSR1SUV39H2 | |
| SCHEMBL15740380 | 0.84 | SSTR5 (0.34) | TMEM97MAPK1NPSR1 | |
| SCHEMBL15740465 | 0.84 | MAOA (0.35) | TMEM97 | |
| SCHEMBL15740425 | 0.83 | TMEM97 (0.34) | TMEM97MAPK1NPSR1 | |
| SCHEMBL15740354 | 0.82 | TMEM97 (0.34) | TMEM97MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |