Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740430 | 0.91 | MAPK1 (0.37) | MAOATMEM97ARHRH3 | |
| SCHEMBL15740416 | 0.91 | TMEM97 (0.34) | TMEM97ARROCK2HRH3 | |
| SCHEMBL15740401 | 0.90 | TMEM97 (0.37) | TMEM97ARHRH3 | |
| SCHEMBL15740486 | 0.86 | TMEM97 (0.37) | TMEM97ARHRH3 | |
| SCHEMBL15740443 | 0.86 | TMEM97 (0.37) | TMEM97HRH3 | |
| SCHEMBL15740425 | 0.85 | TMEM97 (0.34) | TMEM97AR | |
| SCHEMBL15708179 | 0.84 | MAOA (0.36) | MAOATMEM97ARHRH3 | |
| SCHEMBL15727641 | 0.84 | MAOA (0.36) | MAOATMEM97ARHRH3 | |
| SCHEMBL15740369 | 0.84 | TMEM97 (0.34) | TMEM97 | |
| SCHEMBL15740349 | 0.84 | SSTR5 (0.34) | TMEM97ARSSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |