Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740427 | 0.93 | TMEM97 (0.34) | MAPK1NPSR1TMEM97SSTR5 | |
| SCHEMBL15740380 | 0.93 | SSTR5 (0.34) | MAPK1NPSR1TMEM97SSTR5PTGES | |
| SCHEMBL15740408 | 0.89 | PTGES (0.38) | MAPK1NPSR1TMEM97SERPINE1PTGES | |
| SCHEMBL15740430 | 0.88 | MAPK1 (0.37) | MAPK1NPSR1TMEM97PIM1SERPINE1 | |
| SCHEMBL15740437 | 0.87 | MAPK1 (0.38) | MAPK1NPSR1TMEM97SERPINE1ROCK2 | |
| SCHEMBL15740407 | 0.86 | TMEM97 (0.33) | MAPK1NPSR1TMEM97 | |
| SCHEMBL15740443 | 0.85 | TMEM97 (0.37) | MAPK1NPSR1TMEM97PIM1 | |
| SCHEMBL15740442 | 0.85 | MAPK1 (0.39) | MAPK1NPSR1TMEM97SERPINE1ROCK2 | |
| SCHEMBL15740388 | 0.85 | MAPK1 (0.38) | MAPK1NPSR1TMEM97PIM1SERPINE1 | |
| SCHEMBL15740475 | 0.85 | MAPK1 (0.37) | MAPK1NPSR1TMEM97SERPINE1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |