Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 11/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740499 | 0.93 | TMEM97 (0.40) | TMEM97AR | |
| SCHEMBL15740464 | 0.88 | SIRT6 (0.41) | TMEM97ARMAPK1NPSR1 | |
| SCHEMBL15740427 | 0.85 | TMEM97 (0.34) | TMEM97ARMAPK1NPSR1MCHR1 | |
| SCHEMBL15740440 | 0.85 | KCNH2 (0.36) | TMEM97ARMAPK1NPSR1 | |
| SCHEMBL15740486 | 0.85 | TMEM97 (0.37) | TMEM97AR | |
| SCHEMBL15740442 | 0.85 | MAPK1 (0.39) | TMEM97MAPK1NPSR1MCHR1 | |
| SCHEMBL15740495 | 0.84 | HRH3 (0.34) | TMEM97ARMAPK1MCHR1 | |
| SCHEMBL15740401 | 0.83 | TMEM97 (0.37) | TMEM97ARMAPK1NPSR1 | |
| SCHEMBL15740407 | 0.83 | TMEM97 (0.33) | TMEM97ARMAPK1NPSR1 | |
| SCHEMBL15740382 | 0.83 | TMEM97 (0.33) | TMEM97ARMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |