Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15740443 | 0.93 | TMEM97 (0.37) | TMEM97HRH3CHRM2CHRM4CHRM5 | |
| SCHEMBL15740430 | 0.88 | MAPK1 (0.37) | TMEM97HRH3ARCHRM1 | |
| SCHEMBL15740401 | 0.88 | TMEM97 (0.37) | TMEM97HRH3ARCHRM1 | |
| SCHEMBL15740499 | 0.88 | TMEM97 (0.40) | TMEM97ARHTR2ASLC6A3HTR1A | |
| SCHEMBL15740416 | 0.87 | TMEM97 (0.34) | TMEM97HRH3ARCHRM1 | |
| SCHEMBL15740465 | 0.86 | MAOA (0.35) | TMEM97HRH3AR | |
| SCHEMBL15740427 | 0.85 | TMEM97 (0.34) | TMEM97AR | |
| SCHEMBL15740435 | 0.85 | CCR3 (0.38) | TMEM97AR | |
| SCHEMBL15740382 | 0.84 | TMEM97 (0.33) | TMEM97AR | |
| SCHEMBL15740425 | 0.83 | TMEM97 (0.34) | TMEM97ARCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014081697-A2 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL LIMITED (US) | 2014-05-30 | — | — | WO | disclosed |