Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574069 | 1.00 | MEN1 (0.44) | MEN1MAPK1KMT2ADPP8DPP9 | |
| SCHEMBL21773164 | 0.88 | MEN1 (0.55) | MEN1MAPK1KMT2ADPP8DPP9 | |
| SCHEMBL1574043 | 0.88 | MEN1 (0.55) | MEN1MAPK1KMT2ADPP8DPP9 | |
| SCHEMBL21777609 | 0.88 | MEN1 (0.55) | MEN1MAPK1KMT2ADPP8DPP9 | |
| SCHEMBL1574041 | 0.88 | MEN1 (0.55) | MEN1MAPK1KMT2ADPP8DPP9 | |
| SCHEMBL21777608 | 0.88 | MEN1 (0.55) | MEN1MAPK1KMT2ADPP8DPP9 | |
| SCHEMBL21773167 | 0.88 | MEN1 (0.55) | MEN1MAPK1KMT2ADPP8DPP9 | |
| SCHEMBL23948575 | 0.80 | GRIN2B (0.50) | MEN1KMT2AACHEBACE1BCHE | |
| SCHEMBL19583125 | 0.77 | LTA4H (0.50) | MEN1KMT2ADPP8DPP9DPP7 | |
| SCHEMBL17714473 | 0.77 | LTA4H (0.50) | MEN1KMT2ADPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140085-B1 | AZABICYCLOALKANES AS CCR5 MODULATORS | PHIVCO UK LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| US-6586430-B1 | Administering azabicyclo compounds to treat human immunodeficiency virus infections and respiratory system disorders | PFIZER INC. | 2003-07-01 | — | — | US | disclosed |