SCHEMBL23948575

SCHEMBL23948575

c1ccc(CNC2CC3COCC3C2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 3/20 0.50
FYN P06241 1/20 0.50
ACHE P22303 3/20 0.46
BACE1 P56817 3/20 0.46
BCHE P06276 2/20 0.46
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM1A O60341 1/20 0.46
MAOA P21397 1/20 0.46
FUCA1 P04066 1/20 0.44
HRH2 P25021 1/20 0.42
ADRA1B P35368 1/20 0.42
OPRK1 P41145 1/20 0.42
SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20528646 0.85 GRIN2B (0.56) GRIN2BFYNACHEBACE1BCHE
SCHEMBL1574067 0.80 MEN1 (0.44) GRIN2BFYNACHEBACE1BCHE
SCHEMBL1574069 0.80 MEN1 (0.44) GRIN2BFYNACHEBACE1BCHE
SCHEMBL28716809 0.79 GRIN2B (0.55) GRIN2BFYNACHEBACE1BCHE
SCHEMBL30257992 0.79 GRIN2B (0.55) GRIN2BFYNACHEBACE1BCHE
SCHEMBL19583125 0.79 LTA4H (0.50) GRIN2BFYNACHEBACE1BCHE
SCHEMBL19583124 0.79 LTA4H (0.50) GRIN2BFYNACHEBACE1BCHE
SCHEMBL17714473 0.79 LTA4H (0.50) GRIN2BFYNACHEBACE1BCHE
SCHEMBL10039743 0.79 GRIN2B (0.50) GRIN2BFYNACHEBACE1BCHE
SCHEMBL31673699 0.79 FUCA1 (0.47) GRIN2BFYNACHEBACE1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114315834-B Imidazolone derivatives and their use in medicine 成都百裕制药股份有限公司 2024-01-05 CN disclosed
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) 2023-06-01 US disclosed
EP-4137491-A1 IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE Chengdu Baiyu Pharmaceutical Co., Ltd. (CN) 2023-02-22 EP disclosed
CN-114315834-A Imidazolidinone derivatives and their use in medicaments 成都百裕制药股份有限公司 2022-04-12 CN disclosed
WO-2021209055-A1 IMIDAZOLINONE DERIVATIVE AND USE THEREOF IN MEDICINE 成都百裕制药股份有限公司 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165867-A1 IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF SYMPK, PAICS, CYP2C9 GRIN2B 3169/4885FYN 686/4885ACHE 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.