⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901559 | 0.85 | — | — | |
| SCHEMBL1356515 | 0.82 | ACE (0.40) | — | |
| SCHEMBL18135600 | 0.80 | ACE (0.31) | — | |
| SCHEMBL14393087 | 0.80 | ACE (0.31) | — | |
| SCHEMBL11926995 | 0.80 | — | — | |
| SCHEMBL9927941 | 0.79 | CHRNB2 (0.31) | — | |
| SCHEMBL13043015 | 0.77 | — | — | |
| SCHEMBL12041279 | 0.74 | L3MBTL1 (0.34) | — | |
| SCHEMBL12041280 | 0.74 | — | — | |
| SCHEMBL14409234 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2960238-B1 | MONOCYCLIC PYRIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2017-04-05 | — | — | EP | disclosed |
| EP-1673399-B1 | DETECTING AND PROFILING MOLECULAR COMPLEXES | MONOGRAM BIOSCIENCES INC (US) | 2017-04-05 | — | — | EP | disclosed |
| US-9388212-B2 | Solid phase peptide synthesis via side chain attachment | CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) | 2016-07-12 | — | — | US | disclosed |
| EP-2960238-A1 | MONOCYCLIC PYRIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2015-12-30 | — | — | EP | disclosed |
| US-20140235789-A1 | SOLID PHASE PEPTIDE SYNTHESIS VIA SIDE CHAIN ATTACHMENT | CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) | 2014-08-21 | — | — | US | disclosed |
| EP-2735616-A1 | PRODUCTION METHOD FOR CASEIN-DERIVED PEPTIDES BY LACTIC ACID FERMENTATION | Calpis Co., Ltd. (JP) | 2014-05-28 | — | — | EP | disclosed |
| US-20110294813-A1 | OXAZOLIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SHIONOGI & CO., LTD. (JP) | 2011-12-01 | — | — | US | disclosed |