SCHEMBL15744387

SCHEMBL15744387

CCCc1ccc(-c2ccc(-c3ccc(C(F)(F)Br)cc3)c(F)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.43
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40
KIF11 P52732 1/20 0.40
MAOB P27338 2/20 0.40
APP P05067 1/20 0.39
RORC P51449 6/20 0.38
MCL1 Q07820 1/20 0.38
RORA P35398 1/20 0.37
NR1H4 Q96RI1 1/20 0.37
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
GRM2 Q14416 1/20 0.36
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
GFER P55789 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10603849 0.88 RARB (0.51) RARBRARARARGKIF11MAOB
SCHEMBL9512294 0.88 RARB (0.51) RARBRARARARGKIF11MAOB
SCHEMBL20202978 0.86 RARB (0.50) RARBRARARARGKIF11MAOB
SCHEMBL1814580 0.86 RARB (0.40) RARBRARARARGKIF11MAOB
SCHEMBL15744390 0.85 RARB (0.41) RARBRARARARGKIF11MAOB
SCHEMBL9999852 0.83 RARB (0.48) RARBRARARARGKIF11MAOB
SCHEMBL11957382 0.83 RARB (0.48) RARBRARARARGKIF11MAOB
SCHEMBL21741386 0.83 MAOB (0.49) RARBRARARARGKIF11MAOB
SCHEMBL30232659 0.83 RARB (0.48) RARBRARARARGKIF11MAOB
SCHEMBL18708400 0.83 MAOB (0.49) RARBRARARARGKIF11MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
EP-2735599-B1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORP (JP) 2015-04-29 EP disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 EP disclosed