SCHEMBL1814580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18156632	0.91	PDK2 (0.40)	RARBRARARARGPDK2NPC1
	SCHEMBL1810880	0.91	RARB (0.52)	RARBRARARARGTP53HSD17B10
	SCHEMBL13002483	0.90	RARB (0.41)	RARBRARARARGMCL1KIF11
	SCHEMBL16562701	0.90	RARB (0.41)	RARBRARARARGMCL1KIF11
	SCHEMBL12622892	0.89	RARB (0.51)	RARBRARARARGTP53HSD17B10
	SCHEMBL15744320	0.89	S1PR1 (0.35)	RARBRARARARGMCL1KIF11
	SCHEMBL13002330	0.89	RARB (0.40)	RARBRARARARGMCL1KIF11
	SCHEMBL13002742	0.89	RARB (0.40)	RARBRARARARGMCL1KIF11
	SCHEMBL18156631	0.88	KIF11 (0.39)	RARBRARARARGKIF11PDK2
	SCHEMBL19775414	0.88	RARB (0.38)	RARBRARARARGMCL1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.