SCHEMBL1574446

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1575188	0.91	GRIN2B (0.60)	GRIN2BCYP1A2CYP2C9FAAHLMNA
	SCHEMBL1574527	0.91	GRIN2B (0.49)	GRIN2BP2RX1TACR1TRPA1CYP1A2
	SCHEMBL1575155	0.86	UBE2M (0.42)	GRIN2BFAAHUBE2MDCUN1D1
	SCHEMBL1575133	0.86	HPGD (0.52)	GRIN2BCYP2C9FAAHHTT
	SCHEMBL1574385	0.85	GRIN2B (0.54)	GRIN2BP2RX1TACR1CYP1A2USP2
	SCHEMBL1574645	0.85	NPC1 (0.47)	GRIN2BFAAHUBE2MDCUN1D1
	SCHEMBL1574990	0.84	NPSR1 (0.47)	GRIN2BLMNAGAAUBE2MDCUN1D1
	SCHEMBL1575548	0.83	GRIN2B (0.58)	GRIN2BCYP1A2CYP2C9FAAHLMNA
	SCHEMBL1575208	0.83	GRIN2B (0.54)	GRIN2BPAX8FAAHLMNAGAA
	SCHEMBL1575347	0.82	NPC1 (0.53)	CYP1A2USP2CYP2C9PAX8FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.