Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17707467 | 0.93 | TDP1 (0.56) | TDP1USP2ABCB1SMN1; SMN2LMNA | |
| SCHEMBL29535405 | 0.90 | TDP1 (0.74) | TDP1USP2ABCB1SMN1; SMN2LMNA | |
| SCHEMBL5465593 | 0.85 | TDP1 (0.56) | TDP1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7485516 | 0.85 | USP2 (0.56) | USP2ABCB1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18055614 | 0.84 | TDP1 (0.53) | TDP1SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL2010417 | 0.82 | USP2 (0.67) | USP2ABCB1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17707466 | 0.81 | FKBP1A (0.56) | TDP1USP2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15745135 | 0.80 | ALDH1A1 (0.49) | TDP1USP2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15744661 | 0.80 | PTPN1 (0.48) | TDP1SMN1; SMN2LMNAALDH1A1PTPN1 | |
| SCHEMBL15257598 | 0.79 | TDP1 (0.60) | TDP1USP2SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2926121-B1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | OPTI MEDICAL SYSTEMS INC (US) | 2017-02-22 | — | — | EP | disclosed |
| US-9360474-B2 | Multi-layer device for selectively determining magnesium ion | OPTI MEDICAL SYSTEMS, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-9360474-B2 | Multi-layer device for selectively determining magnesium ion | OPTI MEDICAL SYSTEMS, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-20140147876-A1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | IDEXX LABORATORIES, INC. (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140147876-A1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | IDEXX LABORATORIES, INC. (US) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140147876-A1 | MULTI-LAYER DEVICE FOR SELECTIVELY DETERMINING MAGNESIUM ION | ORAI1, CACYBP, CASR | TDP1 3925/4885USP2 4191/4885ABCB1 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.