SCHEMBL15744846

SCHEMBL15744846

CCCc1ccc2cc(-c3ccc(COc4cc(F)c(C(F)(F)OC(F)(F)F)c(F)c4)cc3)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 5/20 0.35
FFAR1 O14842 4/20 0.35
HRH3 Q9Y5N1 4/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
PPARA Q07869 2/20 0.32
PTGES O14684 1/20 0.32
MAOB P27338 2/20 0.32
ALOX5 P09917 2/20 0.32
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15744939 1.00 PPARD (0.35) PPARDFFAR1HRH3SENP8SENP7
SCHEMBL15744997 0.95 FFAR1 (0.32) PPARDFFAR1HRH3SENP8SENP7
SCHEMBL15745088 0.91 HDAC1 (0.38) PPARDFFAR1HRH3MAOB
SCHEMBL15744943 0.91 S1PR1 (0.36) PPARDFFAR1SENP8SENP7SENP6
SCHEMBL15744353 0.90 FFAR4 (0.32) PPARDFFAR1HRH3NPC1TP53
SCHEMBL15744498 0.89 HRH3 (0.38) HRH3NPC1TP53PKMRAB9A
SCHEMBL15744305 0.88 SENP8 (0.41) HRH3SENP8SENP7SENP6MAOB
SCHEMBL15745117 0.87 FFAR1 (0.32) FFAR1
SCHEMBL15744940 0.87 FFAR4 (0.32)
SCHEMBL15745164 0.85 HRH3 (0.34) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed