SCHEMBL15744305

SCHEMBL15744305

CCCc1ccc(COc2cc(F)c(C(F)(F)OC(F)(F)F)c(F)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
MAOB P27338 8/20 0.40
GPR84 Q9NQS5 1/20 0.37
MAOA P21397 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
PTPRZ1 P23471 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15744344 0.93 SENP8 (0.37) SENP8SENP7SENP6MAOBGPR84
SCHEMBL15744939 0.88 PPARD (0.35) SENP8SENP7SENP6MAOBHRH3
SCHEMBL15744846 0.88 PPARD (0.35) SENP8SENP7SENP6MAOBHRH3
SCHEMBL7911415 0.87 MAOB (0.46) SENP8SENP7SENP6MAOBGPR84
SCHEMBL15744985 0.87 MAOB (0.34) SENP8SENP7SENP6MAOB
SCHEMBL15744408 0.84 THRB (0.34) GPR84
SCHEMBL15744997 0.83 FFAR1 (0.32) SENP8SENP7SENP6HRH3
SCHEMBL13636537 0.83 MAOB (0.43) SENP8SENP7SENP6MAOBGPR84
SCHEMBL15744817 0.82 MRGPRX4 (0.32) SENP8SENP7SENP6
SCHEMBL15744316 0.81 RARB (0.39) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-9365774-B2 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-06-14 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
US-20140145113-A1 LIQUID CRYSTAL COMPOUND HAVING CF2OCF3 AT TERMINAL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-29 US disclosed
EP-2735599-A1 Liquid crystal compound having CF2OCF3 at terminal, liquid crystal composition and liquid crystal display device JNC Corporation (JP) 2014-05-28 EP disclosed