Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | HTR2B | P41595 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1E | P28566 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574293 | 0.81 | HTR2C (0.42) | HTR2CHTR2BHTR2AHTR3AMLNR | |
| SCHEMBL15536798 | 0.80 | BCHE (0.44) | MLNR | |
| Hydrochloric Acid SCHEMBL1574477 | 0.80 | SIGMAR1 (0.45) | SIGMAR1ADRB1HTR6IDO1PNMT | |
| Hydrochloric Acid SCHEMBL1574246 | 0.79 | MAOB (0.41) | HTR2CHTR2BHTR2AHTR3ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL9256860 | 0.76 | ALDH1A1 (0.41) | MLNR | |
| SCHEMBL13939515 | 0.75 | DPP7 (0.44) | HTR2CHTR2BHTR2AHTR3ASIGMAR1 | |
| SCHEMBL25344328 | 0.71 | HTR2C (0.53) | HTR2CHTR2BHTR2AHTR3ASIGMAR1 | |
| SCHEMBL16322736 | 0.71 | HTR2C (0.48) | HTR2CHTR2BHTR2AHTR3ASIGMAR1 | |
| SCHEMBL29366568 | 0.70 | ALDH1A1 (0.36) | HTR3ASIGMAR1HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL4887672 | 0.69 | HTR2C (0.47) | HTR2CHTR2BHTR2AHTR3ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618133-B2 | Aralkyl alcohol pyridine derivative compounds and the use thereof as medicaments for treating depression | JIANGSU HENGYI PHARMACEUTICAL CO., LTD. (CN) | 2013-12-31 | — | — | US | disclosed |
| US-20110160247-A1 | Aralkyl alcohol piperidine derivative and the use thereof as a medicament for treating depression | JIANGSU GOWORTH INVESTMENT CO. LTD (CN) | 2011-06-30 | — | — | US | disclosed |
| EP-2305644-A1 | ARALKYL ALCOHOL PIPERIDINE DERIVATIVE AND THE USE AS MEDICAMENT FOR TREATING DEPRESSION THEREOF | Jiangsu Goworth Investment Co. Ltd (CN) | 2011-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160247-A1 | Aralkyl alcohol piperidine derivative and the use thereof as a medicament for treating depression | DRD4, DRD5, DRD3 | HTR2C 22/4885HTR2B 38/4885HTR2A 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.