Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.68 |
| ▸ | BRD4 | O60885 | 5/20 | 0.63 |
| ▸ | BRD2 | P25440 | 5/20 | 0.63 |
| ▸ | BRD3 | Q15059 | 5/20 | 0.63 |
| ▸ | CCKAR | P32238 | 2/20 | 0.62 |
| ▸ | CCKBR | P32239 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574507 | 1.00 | SENP1 (0.68) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL1574340 | 0.95 | SENP1 (0.75) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL1574343 | 0.95 | SENP1 (0.75) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL8556281 | 0.88 | SENP1 (0.59) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL6934495 | 0.87 | SENP1 (0.72) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL1574324 | 0.85 | BRD4 (0.63) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL1574321 | 0.85 | BRD4 (0.63) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL8939417 | 0.85 | SENP1 (0.79) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL8711261 | 0.85 | SENP1 (0.79) | SENP1BRD4BRD2BRD3CCKAR | |
| SCHEMBL8711263 | 0.85 | SENP1 (0.79) | SENP1BRD4BRD2BRD3CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342719-B1 | Benzodiazepine derivatives useful as CCK-Receptor Antagonists | FERRING BV (NL) | 2011-04-13 | — | — | EP | disclosed |
| US-5962451-A | GASTROINTESTINAL DISORDERS; ANTIULCER AGENT; ANTICANCER AGENTS; SIDE-EFFECT REDUCTION | FERRING BV (NL) | 1999-10-05 | — | — | US | disclosed |
| US-5688943-A | CHOLECYSTOKININ ANTAGONIST; ANTIULCER AGENTS; PSYCHOLOGICAL DRUGS; ANXIOLYTIC AGENTS; CONTROLLING APPETITE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| WO-1993016999-A1 | BENZODIAZEPIN DERIVATIVES USEFUL AS CCK-RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |