Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19229970 | 1.00 | KDM4E (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL22872306 | 0.80 | CA1 (0.32) | — | |
| SCHEMBL16510366 | 0.80 | TGFBR1 (0.31) | — | |
| SCHEMBL13631881 | 0.80 | TGFBR1 (0.31) | — | |
| SCHEMBL10061083 | 0.80 | CA1 (0.32) | — | |
| SCHEMBL13227959 | 0.80 | TGFBR1 (0.31) | — | |
| SCHEMBL26352875 | 0.80 | CA1 (0.32) | — | |
| SCHEMBL3923217 | 0.80 | MAPT (0.54) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL560422 | 0.80 | MAPT (0.54) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL25962782 | 0.80 | KDM4E (0.43) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309508-B2 | Boronic and borinic acid compound as inhibitors of sulfenic acid-containing proteins | THE PENN STATE RESEARCH FOUNDATION (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150140635-A1 | Boronic and Borinic Acid Compound as Inhibitors of Sulfenic Acid-Containing Proteins | THE PENN STATE RESEARCH FOUNDATION | 2015-05-21 | — | — | US | disclosed |
| US-8980544-B2 | Boronic and borinic acid compounds as inhibitors of sulfenic acid-containing proteins | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140147905-A1 | Boronic and Borinic Acid Compounds as Inhibitors of Sulfenic Acid-Containing Proteins | THE PENN STATE RESEARCH FOUNDATION | 2014-05-29 | — | — | US | disclosed |