Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923217 | 1.00 | MAPT (0.54) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL560423 | 1.00 | MAPT (0.54) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL1396850 | 0.83 | MAPT (0.50) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL25962782 | 0.82 | KDM4E (0.43) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL30612980 | 0.81 | ACE (0.48) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL27400867 | 0.80 | SMN1; SMN2 (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL15745110 | 0.80 | KDM4E (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL10540962 | 0.80 | SMN1; SMN2 (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL19229970 | 0.80 | KDM4E (0.38) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL24513378 | 0.79 | KDM4E (0.47) | MAPTKDM4ETHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001922-A1 | PEPTIDES TARGETING SODIUM CHANNELS TO TREAT PAIN | UNIV CALIFORNIA (US) | 2026-01-01 | — | — | US | claimed |
| CN-118239879-A | Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine | 泰山学院 | 2024-06-25 | — | — | CN | claimed |
| WO-2024011119-A2 | PEPTIDES TARGETING SODIUM CHANNELS TO TREAT PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-11 | — | — | WO | claimed |
| EP-3365354-B1 | PEPTIDES AND PEPTIDOMIMETICS IN COMBINATION WITH T CELL ACTIVATING AND/OR CHECKPOINT INHIBITING AGENTS FOR CANCER TREATMENT | CANBAS CO LTD (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20260001922-A1 | PEPTIDES TARGETING SODIUM CHANNELS TO TREAT PAIN | UNIV CALIFORNIA (US) | 2026-01-01 | — | — | US | disclosed |
| CN-118239879-A | Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine | 泰山学院 | 2024-06-25 | — | — | CN | disclosed |
| WO-2024011119-A2 | PEPTIDES TARGETING SODIUM CHANNELS TO TREAT PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-11 | — | — | WO | disclosed |
| US-11560359-B2 | Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression | NEW YORK UNIVERSITY (US) | 2023-01-24 | — | — | US | disclosed |
| US-20220183291-A1 | COMPOSITIONS AND METHODS FOR MODULATING IMMUNITY IN PLANTS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. | 2022-06-16 | — | — | US | disclosed |
| US-20210171473-A1 | OXOPIPERAZINE HELIX MIMETICS FOR CONTROL OF HYPOXIA-INDUCIBLE GENE EXPRESSION | UNIV NEW YORK (US) | 2021-06-10 | — | — | US | disclosed |
| CN-112638366-A | Metabolizable pH-sensitive polymersome | UCL商业有限公司 | 2021-04-09 | — | — | CN | disclosed |
| EP-1109827-A2 | BIOACTIVE PEPTIDES | ALPHARMA AS (NO) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012542-A2 | CYTOTOXIC LACTOFERRIN DERIVATIVES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES | ALPHARMA AS (NO) | 2000-03-09 | — | — | WO | disclosed |
| US-5612036-A | CROSSLINKED POLYPEPTIDE VACCINE WITH CYSTEINE GROUPS AND CARRIERS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 1997-03-18 | — | — | US | disclosed |
| US-5445818-A | Immunization using active cyclic polypeptide having cysteine groups crosslinked | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 1995-08-29 | — | — | US | disclosed |
| EP-0469045-B1 | SYNTHETIC $i(PSEUDOMONAS) $i(AERUGINOSA) PILIN PEPTIDE AND RELATED VACCINES AND DIAGNOSTICS | UNIV ALBERTA (CA) | 1994-06-15 | — | — | EP | disclosed |
| EP-0546063-A1 | TOXIC AGENT PROTECTIVE COMPOUNDS, COMPOSITIONS AND USES | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004024-A2 | TOXIC AGENT PROTECTIVE COMPOUNDS, COMPOSITIONS AND METHOD | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1992-03-19 | — | — | WO | disclosed |
| EP-0469045-A1 | SYNTHETIC -i(PSEUDOMONAS) -i(AERUGINOSA) PILIN PEPTIDE AND RELATED VACCINES AND DIAGNOSTICS. | UNIV ALBERTA (CA) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990013563-A1 | SYNTHETIC PSEUDOMONAS AERUGINOSA PILIN PEPTIDE AND RELATED VACCINES AND DIAGNOSTICS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 1990-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171473-A1 | OXOPIPERAZINE HELIX MIMETICS FOR CONTROL OF HYPOXIA-INDUCIBLE GENE EXPRESSION | CREBBP, CREB1, EP300 | MAPT 4551/4885KDM4E 1240/4885THRB 210/4885 |
| US-20220183291-A1 | COMPOSITIONS AND METHODS FOR MODULATING IMMUNITY IN PLANTS | IFNG, STING1, IRF3 | MAPT 3890/4885KDM4E 3904/4885THRB 4448/4885 |
| US-20260001922-A1 | PEPTIDES TARGETING SODIUM CHANNELS TO TREAT PAIN | TPX2, XBP1, SCN9A | MAPT 3814/4885KDM4E 1772/4885THRB 1416/4885 |
| US-11560359-B2 | Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression | CREBBP, CREB1, EP300 | MAPT 4551/4885KDM4E 1240/4885THRB 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.