Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459461 | 0.74 | KCNH2 (0.61) | KCNH2LTB4R | |
| SCHEMBL29028490 | 0.74 | KCNH2 (0.61) | KCNH2LTB4R | |
| SCHEMBL5809787 | 0.73 | CCNE2 (0.34) | KCNH2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL1574516 | 0.72 | KCNH2 (0.50) | KCNH2LTB4R | |
| SCHEMBL4566027 | 0.72 | KCNH2 (0.35) | KCNH2CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL25438253 | 0.72 | KCNH2 (0.59) | KCNH2LTB4R | |
| SCHEMBL10531797 | 0.72 | KCNH2 (0.64) | KCNH2LTB4R | |
| SCHEMBL31026592 | 0.72 | KCNH2 (0.64) | KCNH2LTB4R | |
| SCHEMBL10511946 | 0.72 | KCNH2 (0.64) | KCNH2LTB4R | |
| SCHEMBL10338656 | 0.70 | KCNH2 (0.55) | KCNH2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305274-A1 | Use of WNT stimulators for treating demyelinating diseases | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-04-06 | — | — | EP | disclosed |