Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459407 | 0.98 | CCR1 (0.54) | KCNH2CCR1NOS2PDE10ALTB4R | |
| SCHEMBL30285975 | 0.98 | CCR1 (0.54) | KCNH2CCR1NOS2PDE10ALTB4R | |
| SCHEMBL432244 | 0.98 | CCR1 (0.54) | KCNH2CCR1NOS2PDE10ALTB4R | |
| SCHEMBL29028490 | 0.96 | KCNH2 (0.61) | KCNH2CCR1NOS2PDE10ALTB4R | |
| SCHEMBL30459461 | 0.96 | KCNH2 (0.61) | KCNH2CCR1NOS2PDE10ALTB4R | |
| SCHEMBL25438253 | 0.94 | KCNH2 (0.59) | KCNH2CCR1NOS2PDE10ALTB4R | |
| SCHEMBL22200840 | 0.94 | CCR1 (0.50) | KCNH2CCR1NOS2PDE10ALTB4R | |
| SCHEMBL31026592 | 0.94 | KCNH2 (0.64) | KCNH2CCR1LTB4RESR1 | |
| SCHEMBL10531797 | 0.94 | KCNH2 (0.64) | KCNH2CCR1LTB4RESR1 | |
| SCHEMBL10511946 | 0.94 | KCNH2 (0.64) | KCNH2CCR1LTB4RESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2096578-A | — | — | None | — | — | JP | disclosed |
| JP-H0296578-A | PHENANTHROLINE DERIVATIVE USEFUL AS SENSITIZER FOR ION-SELECTIVE ELECTRODE | AGENCY OF IND SCIENCE & TECHNOL | 1990-04-09 | — | — | JP | disclosed |