Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459461 | 1.00 | KCNH2 (0.61) | KCNH2CCR1LTB4RPDE10ATDP1 | |
| SCHEMBL31026592 | 0.98 | KCNH2 (0.64) | KCNH2CCR1LTB4RESR1ADRA2A | |
| SCHEMBL25438253 | 0.98 | KCNH2 (0.59) | KCNH2CCR1LTB4RPDE10ATDP1 | |
| SCHEMBL10531797 | 0.98 | KCNH2 (0.64) | KCNH2CCR1LTB4RESR1ADRA2A | |
| SCHEMBL10511946 | 0.98 | KCNH2 (0.64) | KCNH2CCR1LTB4RESR1ADRA2A | |
| SCHEMBL10338656 | 0.96 | KCNH2 (0.55) | KCNH2CCR1LTB4RPDE10AMCHR1 | |
| SCHEMBL30285975 | 0.93 | CCR1 (0.54) | KCNH2CCR1LTB4RPDE10AMCHR1 | |
| SCHEMBL432244 | 0.93 | CCR1 (0.54) | KCNH2CCR1LTB4RPDE10AMCHR1 | |
| SCHEMBL30459407 | 0.93 | CCR1 (0.54) | KCNH2CCR1LTB4RPDE10AMCHR1 | |
| SCHEMBL22200840 | 0.89 | CCR1 (0.50) | KCNH2CCR1LTB4RPDE10AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354958-A | Preparation method of 2, 9-disubstituted-1, 2,3, 4-tetrahydro-1, 10-phenanthroline compound | 浙江工业大学 | 2023-06-30 | — | — | CN | disclosed |