SCHEMBL15745480

SCHEMBL15745480

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5ccc6c7cccc(-c8ccccc8)c7sc6c54)cc3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LIMK1 P53667 1/20 0.38
▸ ATM Q13315 3/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ DUSP3 P51452 1/20 0.34
▸ MAPK14 Q16539 1/20 0.33
▸ ALOX5 P09917 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ NFKB2 Q00653 1/20 0.31
▸ RELA Q04206 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25585599 0.99 LIMK1 (0.37) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585481 0.98 L3MBTL1 (0.39) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585502 0.97 L3MBTL1 (0.38) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585483 0.97 L3MBTL1 (0.38) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585402 0.94 ATM (0.35) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585401 0.94 ATM (0.35) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585418 0.94 ATM (0.35) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585603 0.93 ALOX5 (0.34) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585501 0.92 KDM4E (0.35) LIMK1ATMKDM4EL3MBTL1DUSP3
SCHEMBL25585503 0.92 KDM4E (0.35) LIMK1ATMKDM4EL3MBTL1DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 — — US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 — — US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 — — US disclosed
US-9166175-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-10-20 — — US disclosed
US-9166175-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-10-20 — — US disclosed
US-20140145151-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 — — US disclosed
US-20140145151-A1 Organic Electroluminescent Device With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 — — US disclosed
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